| Categoría: Revista Española de Cardiología - Blog

Introduction

The PROMISE trial is an NHLBI-funded randomized comparative effectiveness trial that compared anatomic testing (≥ 64 detector CT angiography) versus functional testing (exercise ECG, stress nuclear, or stress echocardiography) as the initial diagnostic test in patients with new onset symptoms suspicious for coronary artery disease in whom clinicians required diagnostic testing for further evaluation. An economic substudy was conducted to assess economic outcomes and cost effectiveness from a US societal perspective.

| Categoría: Revista Española de Cardiología - Blog

Introduction

There is a need of cardiac protective strategies for high risk patients undergoing cardiac surgery. Remote ischemic conditioning (RIC) supposes a simple non-invasive and low-cost intervention that may improve long-term clinical outcomes in this setting.

| Categoría: Revista Española de Cardiología - Blog

Introduction

Clinical stroke after TAVR is frequent (4-7% at 30 days in RCTs), generally under-reported (17% after SAVR when evaluated by neurologist), confers 3- to 9-fold increased risk of mortality and 50% occurs peri-procedural. Silent stoke affects 58-100% of patients and are associated with neurocognitive decline, dementia and stroke.

| Categoría: Revista Española de Cardiología - Blog

Introduction

Degenerative MR is common, affecting ~600,000 persons in the U.S. Surgery is the standard of care, and is indicated for patients with symptoms or LV dysfunction. However, there are patients in whom the risk of surgery is prohibitive. The Mitraclip system received commercial approval in October 24, 201, being indicated for symptomatic patients with primary MR ≥3 and prohibitive surgical risk. Our objective was to analyze and report the initial commercial experience with the MitraClip System in the U.S.

| Categoría: Revista Española de Cardiología - Blog

Published in The Lancet.

Introduction

The Placement of Aortic Transcatheter Valves (PARTNER) trial showed that mortality at 1 year, 2 years, and 3 years is much the same with transcatheter aortic valve replacement (TAVR) or surgical aortic valve replacement (SAVR) for high-risk patients with aortic stenosis. We report here the 5-year outcomes.

| Categoría: Revista Española de Cardiología - Blog

Published in NEJM

Introduction

Among patients undergoing mitral-valve surgery, 30 to 50% present with atrial fibrillation, which is associated with reduced survival and increased risk of stroke. Surgical ablation of atrial fibrillation has been widely adopted, but evidence regarding its safety and effectiveness is limited.

| Categoría: Revista Española de Cardiología - Blog

El domingo 15 de marzo de 2015 se reunió la Red de Editores de Revistas Cardiovasculares Iberoamericanas coincidiendo con la celebración del 64 Congreso del ACC en San Diego, con el objetivo de compartir experiencias y poner en marcha distintos proyectos conjuntos.

| Categoría: Revista Española de Cardiología - Blog

Published in JACC

Introduction

Obesity and atrial fibrillation (AF) are dual epidemics that frequently coexist. Weight-loss reduces AF burden; however, whether this is sustained, has a dose effect or is influenced by weight-fluctuation is not known. The aim was to evaluate the long-term impact of weight-loss and weight-fluctuation on rhythm control in obese individuals with atrial fibrillation.

| Categoría: Revista Española de Cardiología - Blog

Introduction

Bendavia reduces ROS generation, protects cardiolipin, and preserves mitochondrial integrity and function in animal models of ischemia/reperfusion. The goal of this phase 2 trial was to assess the safety and efficacy of bendavia in acute myocardial infarction in humans.

| Categoría: Revista Española de Cardiología - Blog

Introduction

The SAPIEN 3 TAVR system is the newest iteration of balloon-expandable valve designed with an external fabric skirt to minimize paravalvular regurgitation (PVR). Two non-randomized registries were embedded in the PARTNER II trial to evaluate valve performance.