Date RFP Issued: January 15, 2021
Geographic Scope: all countries except the United States
Clinical Area: Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
Link to full RFP: Junior Investigator Transthyretin Amyloid Cardiomyopathy (ATTR-CM) Research
Application Due Date: March 22, 2021
Specific Area of Interest: Projects that will be considered will aim to improve the understanding of the epidemiology, basic science, early diagnosis and treatment of ATTR-CM through research focused in the following areas:
- Epidemiologic evaluations for ATTR-CM
- Approaches for the early identification and follow up of ATTR-CM patients
- RW efficacy and safety of tafamidis in the clinical setting for the management of ATTR-CM
- Evaluation of patients with ATTR-CM presenting with a mixed phenotype (e.g. cardiomyopathy and polyneuropathy)
- Longitudinal evaluations of neurologic manifestations in patients with ATTR-CM including wild type
- Mechanistic studies to advance the basic science of amyloid formation and deposition on the heart
- Characteristics of ATTR-CM in post-organ transplant patients, including natural course of disease progression
- European country specific early access program data collection